A toxicologic and dermatologic assessment of salicylates when used as fragrance ingredients.

نویسندگان

  • D Belsito
  • D Bickers
  • M Bruze
  • P Calow
  • H Greim
  • J M Hanifin
  • A E Rogers
  • J H Saurat
  • I G Sipes
  • H Tagami
چکیده

An evaluation and review of a structurally related group of fragrance materials.

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An evaluation and review of a structurally related group of fragrance materials.

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The cinnamyl phenylpropyl fragrance ingredients are a diverse group of chemical structures that have similar metabolic and toxicity profiles. A toxicological and dermatological review of these fragrance ingredients is presented. The common characteristic structural element of cinnamyl phenylpropyl materials is an aryl substituted primary alcohol/aldehyde/ester. For high end users, calculated ma...

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A toxicologic and dermatologic assessment of cyclopentanones and cyclopentenones when used as fragrance ingredients.

The cyclopentanone and cyclopentenone group of fragrance ingredients was critically evaluated for safety following a complete literature search. For high end users, calculated maximum dermal exposures vary from 0.002% to 15.16% in hydroalcoholic products; systemic exposures vary from 0.0003 to 0.7122 mg/kg/day. The cyclopentanones and cyclopentenones had a low order of acute toxicity and no sig...

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A toxicologic and dermatologic assessment of ionones

An evaluation and review of a structurally related group of fragrance materials. 2007 Elsevier Ltd. All rights reserved.

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عنوان ژورنال:
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

دوره 45 Suppl 1  شماره 

صفحات  -

تاریخ انتشار 2007